CBGMP (Cannabigerol Monophosphate)

Pharmacokinetics and pharmacology of cannabigerol

The mechanism of action of CBG was until recently unknown. In recent times, novel studies revealed its polypharmacological profile, making it an interesting molecule for direct use as medicament itself or as a possible starting molecular structure for the development of more selective/potent chemical entities.

Pharmacodynamics and pharmacokinetic figures are fundamental for profiling and selecting a drug for medical use. Human CBG exposure and bioavailability are still unknown, but its pharmacokinetics in rodents have been described (Deiana et al., 2012). Plasma and brain pharmacokinetics of CBG (120 mg/kg) were studied in rats and mice, following acute oral and intraperitoneal administration 

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